Dataset Information
Multiomics Characterization of Potential Therapeutic Vulnerabilities in Low-grade Serous Ovarian Carcinoma
Ontology highlight
ABSTRACT:
INSTRUMENT(S):
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture
SUBMITTER: 
Gian Luca Negri
LAB HEAD: Gregg Morin
PROVIDER: PXD019544 | Pride | 2021-05-17
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| TMT_layout.txt | Txt | |||
| sc_27Feb2018_AD_OvC_profiling_A1.raw | Raw | |||
| sc_27Feb2018_AD_OvC_profiling_A10.raw | Raw | |||
| sc_27Feb2018_AD_OvC_profiling_A11.raw | Raw | |||
| sc_27Feb2018_AD_OvC_profiling_A12.raw | Raw |
Items per page: 1 - 5 of 40 |
Publications
Multiomics Characterization of Low-Grade Serous Ovarian Carcinoma Identifies Potential Biomarkers of MEK Inhibitor Sensitivity and Therapeutic Vulnerability.
Cancer research 20210113 7
Low-grade serous ovarian carcinoma (LGSOC) is a rare tumor subtype with high case fatality rates in patients with metastatic disease. There is a pressing need to develop effective treatments using newly available preclinical models for therapeutic discovery and drug evaluation. Here, we use multiomics integration of whole-exome sequencing, RNA sequencing, and mass spectrometry-based proteomics on 14 LGSOC cell lines to elucidate novel biomarkers and therapeutic vulnerabilities. Comparison of LGS ...[more]
