Dataset Information
Deposition for: Mild and Chemoselective, Light-Driven Post-translational Editing Allows Installation of Reactive Side-Chains into Proteins
Ontology highlight
ABSTRACT:
INSTRUMENT(S):
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: 
Simon Nadal
LAB HEAD: Shabaz Mohammed
PROVIDER: PXD019565 | Pride | 2020-09-24
REPOSITORIES: Pride
Dataset's files
Items per page: 1 - 5 of 74 |
Publications
Light-driven post-translational installation of reactive protein side chains.
Nature 20200923 7826
Post-translational modifications (PTMs) greatly expand the structures and functions of proteins in nature<sup>1,2</sup>. Although synthetic protein functionalization strategies allow mimicry of PTMs<sup>3,4</sup>, as well as formation of unnatural protein variants with diverse potential functions, including drug carrying<sup>5</sup>, tracking, imaging<sup>6</sup> and partner crosslinking<sup>7</sup>, the range of functional groups that can be introduced remains limited. Here we describe the visi ...[more]
