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Serum protein abundance of MDR-TB patients based on PRM analysis

ABSTRACT: A mass spectrometry strategy of parallel reaction monitoring was used to detect and validate differential proteins in serum. Here are the data including 3 groups of MDR-TB, DS-TB and HC.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Serum

DISEASE(S): Multidrug-resistant Tuberculosis

SUBMITTER: Jing Chen

LAB HEAD: Ji-Cheng Li

PROVIDER: PXD019604 | Pride | 2020-09-25

REPOSITORIES: Pride

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Serum sCD14, PGLYRP2 and FGA as potential biomarkers for multidrug-resistant tuberculosis based on data-independent acquisition and targeted proteomics.

Chen Jing J Han Yu-Shuai YS Yi Wen-Jing WJ Huang Huai H Li Zhi-Bin ZB Shi Li-Ying LY Wei Li-Liang LL Yu Yi Y Jiang Ting-Ting TT Li Ji-Cheng JC

Journal of cellular and molecular medicine 20200923 21

Multidrug-resistant tuberculosis (MDR-TB), defined as tuberculosis (TB) resistant to at least isoniazid and rifampicin, is a major concern of TB control worldwide. However, the diagnosis of MDR-TB remains a huge challenge to its prevention and control. To identify new diagnostic methods for MDR-TB, a mass spectrometry strategy of data-independent acquisition and parallel reaction monitoring was used to detect and validate differential serum proteins. The bioinformatic analysis showed that the fu ...[more]

PMID: 32967043

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