Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion Lumos
ORGANISM(S): Allomyrina
SUBMITTER: Byung-gyu kim
LAB HEAD: Eun-Kyung Kim
PROVIDER: PXD019661 | Pride | 2021-09-09
REPOSITORIES: Pride
International journal of molecular sciences 20201112 22
The aim of this study was to identify an anti-obesity peptide from <i>Allomyrina dichotoma</i> and investigate the lipid metabolic mechanism. Enzymatically hydrolyzed <i>A. dichotoma</i> larvae were further separated using tangential flow filtration and consecutive chromatographic processes. Finally, an anti-obesity peptide that showed the highest inhibitory effect on lipid accumulation was obtained, and the sequence was Glu-Ile-Ala-Gln-Asp-Phe-Lys-Thr-Asp-Leu (EIA10). EIA10 decreased lipid aggr ...[more]