Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion Lumos, TripleTOF 5600, Q Exactive HF
ORGANISM(S): Homo Sapiens (human) Mus Musculus (mouse)
TISSUE(S): Cell Culture, Pancreatic Islet Beta Cell, Fibroblast
SUBMITTER: Cheryl Lichti
LAB HEAD: Cheryl Lichti
PROVIDER: PXD019819 | Pride | 2021-02-11
REPOSITORIES: pride
Items per page: 1 - 5 of 28 |
Proteomics 20210305 7-8
Proteasomal spliced peptides (PSPs) have been identified in the class I major histocompatibility complex (MHC) peptidomes of several tumors and have emerged as novel neoantigens that can stimulate highly specific T cells. Much debate has surrounded the percentage of PSPs in the immunopeptidome; reported numbers have ranged from <1-5% to 12-45%. Recently, our laboratory demonstrated in nonobese diabetic (NOD) mice that hybrid insulin peptides (HIPs), a special class of spliced peptides, are forme ...[more]