Dataset Information
Analysis of UBASH3B interactome in A549 and in HEK293 Flpin cell lines
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion Lumos, Orbitrap Fusion
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: 
Federico Uliana
LAB HEAD: Ruedi Aebersold
PROVIDER: PXD019878 | Pride | 2022-10-13
REPOSITORIES: Pride
Publications
Novel biochemical, structural, and systems insights into inflammatory signaling revealed by contextual interaction proteomics.
Proceedings of the National Academy of Sciences of the United States of America 20220930 40
Protein-protein interactions (PPIs) represent the main mode of the proteome organization in the cell. In the last decade, several large-scale representations of PPI networks have captured generic aspects of the functional organization of network components but mostly lack the context of cellular states. However, the generation of context-dependent PPI networks is essential for structural and systems-level modeling of biological processes-a goal that remains an unsolved challenge. Here we describ ...[more]