Dataset Information
Targeted multiplexed proteomics of SARS-CoV-2 peptides in ALI cells
Ontology highlight
ABSTRACT:
INSTRUMENT(S):
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Lung
SUBMITTER: 
Kevin Klann
LAB HEAD: Christian Münch
PROVIDER: PXD019950 | Pride | 2020-11-05
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| 20200621_KKL_CoV2_Targeted_MS2_new-1.msf | Msf | |||
| 20200621_KKL_CoV2_Targeted_MS2_new.raw | Raw | |||
| Mass_list_02.txt | Txt |
Items per page: 1 - 3 of 3 |
Publications
Aprotinin Inhibits SARS-CoV-2 Replication.
Cells 20201030 11
Severe acute respiratory syndrome virus 2 (SARS-CoV-2) is the cause of the current coronavirus disease 19 (COVID-19) pandemic. Protease inhibitors are under consideration as virus entry inhibitors that prevent the cleavage of the coronavirus spike (S) protein by cellular proteases. Herein, we showed that the protease inhibitor aprotinin (but not the protease inhibitor SERPINA1/alpha-1 antitrypsin) inhibited SARS-CoV-2 replication in therapeutically achievable concentrations. An analysis of prote ...[more]
