The gut bacterium Extibacter muris produces secondary bile acids and influences liver physiology in gnotobiotic mice - Proteomics results

ABSTRACT: In this study, mice were colonized from birth on with the minimal microbiota Oligo-MM with or without the addition of Extibacter muris. Extibacter muris is known to metabolize cholic acid to deoxycholic acid via 7α-dehydroxylation. The impact of Extibacter muris colonization on the liver proteome of mice under different diets was investigated using untargeted proteomics.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Liver

SUBMITTER: Isabel Karkossa  

LAB HEAD: Kristin Schubert

PROVIDER: PXD019973 | Pride | 2021-01-04

REPOSITORIES: Pride