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NFU3 is an Fe-S cluster carrier protein that is implicated in photosystem I maturation (PsaA, PsaB, PsaC). Label free proteomic approach on nfu3-2 mutant allow the discovery of new potential client proteins

ABSTRACT: NFU3 is a Fe-S cluster carrier protein of Arabidopsis that allow the maturation of Fe-S cluster proteins in chloroplast. proteomic Label free experiment was carried out to monitored wich Fe-S cluster proteins are affected in nfu3-2 mutant background

INSTRUMENT(S): Q Exactive

ORGANISM(S): Arabidopsis Thaliana (mouse-ear Cress)

TISSUE(S): Plant Cell, Cotyledon, Root

SUBMITTER: Nathalie Berger

LAB HEAD: Christian Dubos

PROVIDER: PXD020228 | Pride | 2021-09-09

REPOSITORIES: Pride

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A Global Proteomic Approach Sheds New Light on Potential Iron-Sulfur Client Proteins of the Chloroplastic Maturation Factor NFU3.

Berger Nathalie N Vignols Florence F Touraine Brigitte B Taupin-Broggini Maël M Rofidal Valérie V Demolombe Vincent V Santoni Véronique V Rouhier Nicolas N Gaymard Frédéric F Dubos Christian C

International journal of molecular sciences 20201030 21

Iron-sulfur (Fe-S) proteins play critical functions in plants. Most Fe-S proteins are synthetized in the cytosol as apo-proteins and the subsequent Fe-S cluster incorporation relies on specific protein assembly machineries. They are notably formed by a scaffold complex, which serves for the de novo Fe-S cluster synthesis, and by transfer proteins that insure cluster delivery to apo-targets. However, scarce information is available about the maturation pathways of most plastidial Fe-S proteins an ...[more]

PMID: 33143294

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