Proteomics

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Protein identification of venoms of the African spitting Cobras, Naja mossambica and Naja nigricincta nigricincta


ABSTRACT: Venoms of Naja mossambica and Naja nigricincta nigricincta were analysed in order to identify the proteins. Samples were run on SDS-PAGE gel or analysed without digestion.

INSTRUMENT(S): Q Exactive HF, Q Exactive

ORGANISM(S): Naja Nigricincta Nigricincta Naja Mossambica

TISSUE(S): Venom

SUBMITTER: Mirva Pääkkönen  

LAB HEAD: Peter James

PROVIDER: PXD020411 | Pride | 2020-08-25

REPOSITORIES: Pride

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Publications

Protein Identification of Venoms of the African Spitting Cobras, <i>Naja mossambica</i> and <i>Naja nigricincta nigricincta</i>.

Katali Ottilie O   Shipingana Loide L   Nyarangó Peter P   Pääkkönen Mirva M   Haindongo Erastus E   Haindongo Erastus E   Rennie Timothy T   James Peter P   Eriksson John J   Hunter Christian John CJ  

Toxins 20200814 8


Cobra snakes, including <i>Naja mossambica</i> and <i>Naja nigricincta nigricincta,</i> are one of the major groups of snakes responsible for snakebites in southern Africa, producing significant cytotoxicity and tissue damage. The venom of <i>N. mossambica</i> has been briefly characterised, but that of <i>N. n. nigricincta</i> is not reported. The current study identifies the venom proteins of <i>N. mossambica</i> and <i>N. n. nigricincta</i>. This is achieved using sodium dodecyl sulphate (SDS  ...[more]

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