Proteomics

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Evaluation of antifungal activity of Naja pallida and Naja mossambica venoms against three Candida species

ABSTRACT: In contrast to comprehensively investigated antibacterial activity of snake venoms, namely crude venoms and their selected components, little is known about antifungal properties of elapid snake venoms. In the present study, the proteome of two venoms of red spitting cobra Naja pallida (NPV) and Mozambique spitting cobra Naja mossambica (NMV) was characterized using LC-MS/MS approach and the biological activity of crude venoms against three Candida species was established.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Naja Mossambica Naja Pallida

TISSUE(S): Venom

SUBMITTER: Konrad Hus  

LAB HEAD: Aleksandra Bocian

PROVIDER: PXD020450 | Pride | 2020-08-12

REPOSITORIES: Pride

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Evaluation of Antifungal Activity of <i>Naja pallida</i> and <i>Naja mossambica</i> Venoms against Three <i>Candida</i> Species.

Kuna Ewelina E   Bocian Aleksandra A   Hus Konrad K KK   Petrilla Vladimir V   Petrillova Monika M   Legath Jaroslav J   Lewinska Anna A   Wnuk Maciej M  

Toxins 20200804 8

In contrast to comprehensively investigated antibacterial activity of snake venoms, namely crude venoms and their selected components, little is known about antifungal properties of elapid snake venoms. In the present study, the proteome of two venoms of red spitting cobra <i>Naja pallida</i> (NPV) and Mozambique spitting cobra <i>Naja mossambica</i> (NMV) was characterized using LC-MS/MS approach, and the antifungal activity of crude venoms against three <i>Candida</i> species was established.  ...[more]

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