Dataset Information

Mass-spectrometry analysis of the human pineal proteome during night and day and in autism.

ABSTRACT: Using mass spectrometry based proteomics and dedicated analysis tools, we identify proteins expressed in the human pineal gland and analyze systematically their variation with time of the throughout the day, and, compare these changes in the pineal proteome between control specimens and donors diagnosed with ASD.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Basis Pedunculi Cerebri, Interstitial Cell Of Pineal Gland

DISEASE(S): Autism Spectrum Disorder

SUBMITTER: MARIETTE MATONDO

LAB HEAD: MARIETTE MATONDO

PROVIDER: PXD020501 | Pride | 2021-09-09

REPOSITORIES: Pride

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Publications

Mass-spectrometry analysis of the human pineal proteome during night and day and in autism.

Dumas Guillaume G Goubran-Botros Hany H Matondo Mariette M Pagan Cécile C Boulègue Cyril C Chaze Thibault T Chamot-Rooke Julia J Maronde Erik E Bourgeron Thomas T

Journal of pineal research 20210111 3

The human pineal gland regulates day-night dynamics of multiple physiological processes, especially through the secretion of melatonin. Using mass-spectrometry-based proteomics and dedicated analysis tools, we identify proteins in the human pineal gland and analyze systematically their variation throughout the day and compare these changes in the pineal proteome between control specimens and donors diagnosed with autism. Results reveal diverse regulated clusters of proteins with, among others, c ...[more]

PMID: 33368564

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Dataset Information

Mass-spectrometry analysis of the human pineal proteome during night and day and in autism.

Publications

Mass-spectrometry analysis of the human pineal proteome during night and day and in autism.

Similar Datasets

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