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USP15 deubiquitinase safeguards hematopoiesis and genome integrity in hematopoietic stem cells and leukemia cells

ABSTRACT: To decipher the role of USP15 in DNA damage in leukemia cells, endogenous USP15 was immunoprecipitated from MV4-11 and Kasumi-1 cell lines under naive and DNA stress conditions (Mitomycin C, 30nM, 1h). 355 candidates co-immunoprecipitated with USP15 in all the conditions, in 4 independent experiments.

INSTRUMENT(S): Orbitrap Exploris 480

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Leukocyte, Cell Culture

DISEASE(S): Acute Leukemia

SUBMITTER: Oliver Popp

LAB HEAD: Gaetano Gargiulo

PROVIDER: PXD020612 | Pride | 2021-01-04

REPOSITORIES: Pride

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