Tubulin Tyrosine Ligase Like 4 (TTLL4) overexpression in breast cancer cells alters exosome biogenesis and promotes brain metastasis

ABSTRACT: The survival rate is poor in breast cancer patients with brain metastases. Thus, new concepts for therapeutic approaches are required. During metastasis, the cytoskeleton of cancer cells is highly dynamic and therefore cytoskeleton-associated proteins are interesting targets for tumour therapy.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Epithelial Cell, Cell Culture

DISEASE(S): Breast Cancer

SUBMITTER: Christoph Krisp  

LAB HEAD: Sabine Windhorst

PROVIDER: PXD020743 | Pride | 2021-08-20

REPOSITORIES: Pride