Quantitative LC-MS/MS Proteomics of human liver microsomes

ABSTRACT: We report label-free quantification of xenobiotic metabolizing enzymes (XME), transporters, redox enzymes, proteases and nucleases in 20 human liver microsomal samples. More than 3500 proteins were identified and quantified. These data can be used in physiologically based pharmacokinetic models to predict appropriate drug doses for a wide variety of drugs.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Hepatocyte, Liver

SUBMITTER: Jill Barber  

LAB HEAD: Jill Barber

PROVIDER: PXD020910 | Pride | 2021-09-08

REPOSITORIES: Pride