Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion Lumos
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Primary Cell
SUBMITTER: Yasaman Jami-Alahmadi
LAB HEAD: Luisa Iruela-Arispe
PROVIDER: PXD020958 | Pride | 2023-07-20
REPOSITORIES: Pride
Afshar Yalda Y Ma Feyiang F Quach Austin A Jeong Anhyo A Sunshine Hannah L HL Freitas Vanessa V Jami-Alahmadi Yasaman Y Helaers Raphael R Li Xinmin X Pellegrini Matteo M Wohlschlegel James A JA Romanoski Casey E CE Vikkula Miikka M Iruela-Arispe M Luisa ML
eLife 20230327
Environmental cues, such as physical forces and heterotypic cell interactions play a critical role in cell function, yet their collective contributions to transcriptional changes are unclear. Focusing on human endothelial cells, we performed broad individual sample analysis to identify transcriptional drifts associated with environmental changes that were independent of genetic background. Global gene expression profiling by RNA sequencing and protein expression by liquid chromatography-mass spe ...[more]