Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture
SUBMITTER: Takehiro Suzuki
LAB HEAD: Naoshi Dohmae
PROVIDER: PXD021040 | Pride | 2020-11-16
REPOSITORIES: Pride
Ko Kenta K Suzuki Takehiro T Ishikawa Ryota R Hattori Natsuko N Ito Risako R Umehara Kenta K Furihata Tomomi T Dohmae Naoshi N Linhardt Robert J RJ Igarashi Kazuei K Toida Toshihiko T Higashi Kyohei K
The Journal of biological chemistry 20201030 52
Infiltration of peripheral immune cells after blood-brain barrier dysfunction causes severe inflammation after a stroke. Although the endothelial glycocalyx, a network of membrane-bound glycoproteins and proteoglycans that covers the lumen of endothelial cells, functions as a barrier to circulating cells, the relationship between stroke severity and glycocalyx dysfunction remains unclear. In this study, glycosaminoglycans, a component of the endothelial glycocalyx, were studied in the context of ...[more]