Human Neutrophils Phosphoproteome in Systemic Lupus Erythematosus

ABSTRACT: This study used proteomic, biomechanical, and functional analyses to further define neutrophil heterogeneity in the context of SLE. Mass spectrometry proteomic and phosphoproteomic analyses were performed in healthy control normal density neutrophils (NDNs), SLE NDNs and in autologous SLE LDGs. Proteomic and phosphoproteomic differences were detected when comparing control to SLE neutrophils and when comparing SLE NDNs to SLE LDGs.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Neutrophil

DISEASE(S): Systemic Lupus Erythematosus

SUBMITTER: Angel Aponte  

LAB HEAD: Angel Aponte

PROVIDER: PXD021096 | Pride | 2021-11-04

REPOSITORIES: Pride