Proteomics

Dataset Information

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Saliva LC-MS/MS of mouth breathing children


ABSTRACT: Salivary proteins of mouth breathing children were compared with paired nose breathing children using label-free quantification (LFQ). The differentially expressed proteins were screened (fold-change 1.5, p value<0.05).

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Saliva

SUBMITTER: Xianliang Ma  

LAB HEAD: Cancan Fan

PROVIDER: PXD021106 | Pride | 2021-09-09

REPOSITORIES: Pride

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Publications

Alterations in Oral-Nasal-Pharyngeal Microbiota and Salivary Proteins in Mouth-Breathing Children.

Fan Cancan C   Guo Lihong L   Gu Haijing H   Huo Yongbiao Y   Lin Huancai H  

Frontiers in microbiology 20201009


Mouth breathing induces a series of diseases, while the influence on microbiota of oral cavity and salivary proteins remains unknown. In this study, for the first time, profiles of oral-nasal-pharyngeal microbiota among mouth-breathing children (MB group, <i>n</i> = 10) were compared with paired nose-breathing children (NB group, <i>n</i> = 10) using 16S ribosomal DNA (rDNA) (V3-V4 region) high-throughput sequencing. The differentially expressed salivary proteins were revealed using label-free q  ...[more]

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