Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Breast Epithelial Cell, Epithelial Cell, Breast Cancer Cell
DISEASE(S): Breast Cancer
SUBMITTER: Tommaso De Marchi
LAB HEAD: Emma Nimeus
PROVIDER: PXD021394 | Pride | 2021-04-26
REPOSITORIES: Pride
De Marchi Tommaso T Pyl Paul Theodor PT Sjöström Martin M Klasson Stina S Sartor Hanna H Tran Lena L Pekar Gyula G Malmström Johan J Malmström Lars L Niméus Emma E
Journal of proteome research 20210415 5
Proteogenomic approaches have enabled the generat̲ion of novel information levels when compared to single omics studies although burdened by extensive experimental efforts. Here, we improved a data-independent acquisition mass spectrometry proteogenomic workflow to reveal distinct molecular features related to mammographic appearances in breast cancer. Our results reveal splicing processes detectable at the protein level and highlight quantitation and pathway complementarity between RNA and prot ...[more]