Lipid and protein profiles associated to human osteoarthritis type 2 diabetes phenotype

ABSTRACT: Osteoarthritis (OA) is a multifactorial pathology which comprises a wide range of distinct phenotypes. The characterization of the different molecular profiles associated to each phenotype can improve the classification of OA for a better personalized medicine. Within the metabolic syndrome phenotype, OA can co-exist with type 2 diabetes (TD2) disease. This study was undertaken to investigate lipidomic and proteomic differences between human OA and OA/TD2 cartilage through a multimodal mass spectrometry approach.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cartilage

DISEASE(S): Type 2 Diabetes Mellitus

SUBMITTER: freek bouwman  

LAB HEAD: Berta Cillero Pastor

PROVIDER: PXD021487 | Pride | 2021-04-20

REPOSITORIES: Pride