Mitochondrial protein complexes from a patient with mutations in DNAJC30 compared to an age and gender matched healthy control

ABSTRACT: We identified DNAJC30 as a key protein in the maintenance of functional NADH:ubiquinone oxidoreductase (complex I). To determine the consequence of mutations in DNAJC30 on the assembly of complex I we utilized complexome profiling.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture, Fibroblast

SUBMITTER: Ilka Wittig  

LAB HEAD: Holger Prokisch

PROVIDER: PXD021500 | Pride | 2021-09-09

REPOSITORIES: Pride