Proteome for Usp11 knockout E17.5 cortex

ABSTRACT: Since Usp11 encodes a DUB, we reasoned that Usp11 deficiency may lead to increased ubiquitination and destabilization of a protein that functions in neuronal differentiation and migration.To define the molecular mechanism of Usp11 deficiency on cortical development, we performed a label-free quantitative liquid chromatography-tandem Mass Spectrometry (LC-MS/MS) analysis to detect the protein expression profiles in E17.5 WT and Usp11 KO cortices in four biological repeats.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Brain, Generation Of Neurons

SUBMITTER: Shang Yin Chiang  

LAB HEAD: Shang Yin, Chiang

PROVIDER: PXD021587 | Pride | 2021-01-29

REPOSITORIES: Pride