Proteomics

Dataset Information

0

XL-MS data analysis with MeroX and XlinkX


ABSTRACT: Comparison of MeroX in different modes and XlinkX upon variation of database size based on DSBU linked BSA as test-dataset

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Bos taurus  

TISSUE(S): Tissue Not Applicable To Dataset

DISEASE(S): Not Available

SUBMITTER: Manuel Matzinger  

LAB HEAD: Karl Mechtler

PROVIDER: PXD021648 | Pride | 2020-11-17

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
BSA-10000prot-human.fasta Fasta
BSA-1000prot-human.fasta Fasta
BSA-100prot-human.fasta Fasta
BSA-10prot-human.fasta Fasta
BSA-only.fasta Fasta
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Publications

Cleavable Cross-Linkers and Mass Spectrometry for the Ultimate Task of Profiling Protein-Protein Interaction Networks <i>in Vivo</i>.

Matzinger Manuel M   Mechtler Karl K  

Journal of proteome research 20201105 1


Cross-linking mass spectrometry (XL-MS) has matured into a potent tool to identify protein-protein interactions or to uncover protein structures in living cells, tissues, or organelles. The unique ability to investigate the interplay of proteins within their native environment delivers valuable complementary information to other advanced structural biology techniques. This Review gives a comprehensive overview of the current possible applications as well as the remaining limitations of the techn  ...[more]

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