Proteomics

Dataset Information

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Proteogenomics of Hyphomicrobium sp. MC8b strain


ABSTRACT: This project is a proteomic comparison of Hyphomicrobium sp. MC8b grown with dichloromethane or with methanol. The datasets were obtained using the annotated genome of Hyphomicrobium sp. MC8b.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Hyphomicrobium Sp. Mc8b

SUBMITTER: Jean ARMENGAUD  

LAB HEAD: Jean Armengaud

PROVIDER: PXD021817 | Pride | 2021-09-09

REPOSITORIES: Pride

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Publications


Several bacteria are able to degrade the major industrial solvent dichloromethane (DCM) by using the conserved dehalogenase DcmA, the only system for DCM degradation characterised at the sequence level so far. Using differential proteomics, we rapidly identified key determinants of DCM degradation for <i>Hyphomicrobium</i> sp. MC8b, an unsequenced facultative methylotrophic DCM-degrading strain. For this, we designed a pan-proteomics database comprising the annotated genome sequences of 13 disti  ...[more]

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