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A comprehensive landscape of 60S ribosome biogenesis factors

ABSTRACT: We used quantitative proteomics and crosslinking mass spectrometry (XL-MS) to analyse a comprehensive set of purified pre-60S ribosomal particles, obtaining a detailed timeline of RBF engagement during 60S ribosome biogenesis as well as particle-specific crosslink networks for all analysed particles. Our data provide an important resource for all future structural and biochemical studies of 60S ribosome biogenesis.

INSTRUMENT(S): Orbitrap Fusion

ORGANISM(S): Saccharomyces Cerevisiae (baker's Yeast)

SUBMITTER: Florian Stengel

LAB HEAD: Florian Stengel

PROVIDER: PXD021831 | Pride | 2021-12-07

REPOSITORIES: Pride

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