Arg-GlcNAcylation of Salmonella proteins

ABSTRACT: This project explores the impact of SseK mediated Arg-GlcNAcylation on Salmonella proteins. Using Site directed mutagenesis, MS analysis and phenotypic studies we show Arg-GlcNAcylation appears to modulate the functions of multiple salmonella enzymes. This work demonstrates effectors can have multiple roles both within host cells and bacterial pathogens themselves.

INSTRUMENT(S):

ORGANISM(S): Salmonella Enterica Subsp. Enterica Serovar Typhimurium Str. St1489

SUBMITTER: Nichollas Scott  

LAB HEAD: Philip Hardwidge

PROVIDER: PXD021878 | Pride | 2021-09-09

REPOSITORIES: Pride