Proteomics

Dataset Information

Systematic analysis of MYC regulators identifies AKIRIN2 as an essential mediator of nuclear proteasome import

ABSTRACT: AKIRIN2 is an essential negative regulator of MYC protein levels. To test the specificity of AKIRIN2-dependent MYC regulation we performed unbiased protein quantification after inducible AKIRIN2- or Proteasome knockout und identified subsets of proteins accumulating after loss of AKIRIN2, Proteasomes or both.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Colon, Blood

SUBMITTER: Richard Imre  

LAB HEAD: Johannes Zuber

PROVIDER: PXD021898 | Pride | 2021-11-02

REPOSITORIES: pride

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Dataset's files

Source:
Action DRS
20190621_28_QExHFX2-4_Hinterndorfer_Zuber_IMP_sgRKO_TMT11plex_SCX_FR1-140_human_Limma-new.pdResult Other
20190621_QExHFX2_RSLC4_Hinterndorfer_Zuber_IMP_sgRKO_TMT_SCX_10per_FR49.raw Raw
20190621_QExHFX2_RSLC4_Hinterndorfer_Zuber_IMP_sgRKO_TMT_SCX_10per_FR50.raw Raw
20190621_QExHFX2_RSLC4_Hinterndorfer_Zuber_IMP_sgRKO_TMT_SCX_10per_FR51.raw Raw
20190621_QExHFX2_RSLC4_Hinterndorfer_Zuber_IMP_sgRKO_TMT_SCX_10per_FR52.raw Raw
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