The MbovP280 of mycoplasma bovis immunoprecipitates with the wole cell lysates of bovine macrophage (BoMac),and then LC-MS/MS was used to identify the MbovP280-binding ligands
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Bos Taurus (bovine)
TISSUE(S): Cell Culture, Macrophage
SUBMITTER: 
Gang Zhao
LAB HEAD: Aizhen Guo
PROVIDER: PXD022080 | Pride | 2021-09-09
REPOSITORIES: Pride
Publications
Novel Secreted Protein of <i>Mycoplasma bovis</i> MbovP280 Induces Macrophage Apoptosis Through CRYAB.
Zhao Gang G Zhu Xifang X Zhang Hui H Chen Yingyu Y Schieck Elise E Hu Changmin C Chen Huanchun H Guo Aizhen A
Frontiers in immunology 20210215
<i>Mycoplasma bovis</i> causes important diseases and great losses on feedlots and dairy farms. However, there are only a few measures to control <i>M. bovis</i>-related diseases. As in other mycoplasma species, this is predominantly because the virulence related factors of this pathogen are largely unknown. Therefore, in this study, we aimed to identify novel virulence-related factors among the secreted proteins of <i>M. bovis</i>. Using bioinformatic tools to analyze its secreted proteins, we ...[more]
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