Complexome profiling of mitochondrial protein complexes to study the molecular consequences of DNAJC30 mutations in HEK cells

ABSTRACT: We identified the chaperone DNAJC30 as an important factor to maintain NADH:ubiquinone oxidoreductase (complex I) activity. In this complexome analysis we analysed complexes of the oxidative phosphorylation system (OXPHOS) in HEK cells deficient for DNAJC30.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture, Fibroblast

SUBMITTER: Ilka Wittig  

LAB HEAD: Holger Prokisch

PROVIDER: PXD022340 | Pride | 2021-09-09

REPOSITORIES: Pride