Phosphorylation of Rif1 by Plk1
Ontology highlight
ABSTRACT: Polo-like kinase 1 (Plk1) is an important protein kinase for checkpoint recovery and adaptation in response to DNA damage and replication stress. However, although Plk1 is present in S phase, little is known about its localization and function during unperturbed DNA replication. Here used recombinant XRif1 C-terminal domain and recombinant XPlk1 in an in vitro phosphorylation assay followed by LC/MS/MS to identify which residues are phosphorylated by Plk1 on Rif1 CTD.
INSTRUMENT(S): Q Exactive Plus
ORGANISM(S): Xenopus Tropicalis X Xenopus Laevis
TISSUE(S): Oocyte
SUBMITTER: Chiara guerrera
LAB HEAD: Chiara Guerrera
PROVIDER: PXD022410 | Pride | 2021-08-26
REPOSITORIES: Pride
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