Characterization of epiploic adipose tissue
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): White Fat Cell, White Adipose Tissue
DISEASE(S): Type 2 Diabetes Mellitus
SUBMITTER: 
Laura Krieg
LAB HEAD: Kristin Schubert
PROVIDER: PXD022465 | Pride | 2022-12-13
REPOSITORIES: Pride
Publications
Multiomics reveal unique signatures of human epiploic adipose tissue related to systemic insulin resistance.
Krieg Laura L Didt Konrad K Karkossa Isabel I Bernhart Stephan H SH Kehr Stephanie S Subramanian Narmadha N Lindhorst Andreas A Schaudinn Alexander A Tabei Shirin S Keller Maria M Stumvoll Michael M Dietrich Arne A von Bergen Martin M Stadler Peter F PF Laurencikiene Jurga J Krüger Martin M Blüher Matthias M Gericke Martin M Schubert Kristin K Kovacs Peter P Chakaroun Rima R Massier Lucas L
Gut 20211001 11
<h4>Objective</h4>Human white adipose tissue (AT) is a metabolically active organ with distinct depot-specific functions. Despite their locations close to the gastrointestinal tract, mesenteric AT and epiploic AT (epiAT) have only scarcely been investigated. Here, we aim to characterise these ATs in-depth and estimate their contribution to alterations in whole-body metabolism.<h4>Design</h4>Mesenteric, epiploic, omental and abdominal subcutaneous ATs were collected from 70 patients with obesity ...[more]
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