Dataset Information
ULK1 on-bead in vitro kinase assay
Ontology highlight
ABSTRACT:
INSTRUMENT(S):
ORGANISM(S): Mus Musculus (mouse)
SUBMITTER: 
Joern Dengjel
LAB HEAD: Joern Dengjel
PROVIDER: PXD022759 | Pride | 2021-11-03
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| 20201105_ZH_ULK1_ATP_1_01.raw | Raw | |||
| 20201105_ZH_ULK1_ATP_1_02.raw | Raw | |||
| 20201105_ZH_ULK1_ATP_1_03.raw | Raw | |||
| 20201105_ZH_ULK1_ATP_1_04.raw | Raw | |||
| 20201105_ZH_ULK1_ATP_1_05.raw | Raw |
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Publications
ULK1 phosphorylation of striatin activates protein phosphatase 2A and autophagy.
Cell reports 20210901 13
The evolutionarily conserved ULK1 kinase complex acts as gatekeeper of canonical autophagy and regulates induction of autophagosome biogenesis. To better understand control of ULK1 and analyze whether ULK1 has broader functions that are also linked to the later steps of autophagy, we perform comprehensive phosphoproteomic analyses. Combining in vivo with in vitro data, we identify numerous direct ULK1 target sites within autophagy-relevant proteins that are critical for autophagosome maturation ...[more]
