Proteomics

Dataset Information

Identifying a GSK3-TRARG1 signaling axis reveals BCL9L as a novel regulator of GLUT4 trafficking

ABSTRACT: The trafficking regulator of GLUT4-1 (TRARG1) protein positively regulates insulin-stimulated GLUT4 trafficking. Here we identify post-translational modifications on TRARG1 and identify that GSK3 is the upstream kinase responsible for TRARG1 phosphorylation at Serines 72, 76, and 80. We employ affinity enrichment mass spectrometry to identify protein interactions regulated by TRARG1 phosphorylation.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Fat Cell

SUBMITTER: Sean Humphrey  

LAB HEAD: David E James

PROVIDER: PXD022765 | Pride | 2022-08-12

REPOSITORIES: Pride

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Action DRS
20171024_QEplus_BP_Xiaowen_TRARG1_1.raw Raw
20171024_QEplus_BP_Xiaowen_TRARG1_2.raw Raw
20171024_QEplus_BP_Xiaowen_TRARG1_3.raw Raw
20171024_QEplus_BP_Xiaowen_TRARG1_4.raw Raw
20171024_QEplus_BP_Xiaowen_TRARG1_5.raw Raw
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