Dataset Information
Systemic inflammation and metabolic disturbances are central pathways related to mortality of ill severely malnourished children
Ontology highlight
ABSTRACT:
INSTRUMENT(S):
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: 
James Njunge
LAB HEAD: James Njunge
PROVIDER: PXD022792 | Pride | 2022-05-23
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| F75_BATCH1.mgf | Mgf | |||
| F75_BATCH1.raw | Raw | |||
| F75_BATCH10.mgf | Mgf | |||
| F75_BATCH10.raw | Raw | |||
| F75_BATCH11.mgf | Mgf |
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Publications
Systemic inflammation and metabolic disturbances underlie inpatient mortality among ill children with severe malnutrition.
Science advances 20220216 7
Children admitted to hospital with an acute illness and concurrent severe malnutrition [complicated severe malnutrition (CSM)] have a high risk of dying. The biological processes underlying their mortality are poorly understood. In this case-control study nested within a multicenter randomized controlled trial among children with CSM in Kenya and Malawi, we found that blood metabolomic and proteomic profiles robustly differentiated children who died (<i>n</i> = 92) from those who survived (<i>n< ...[more]
