Proteomics

Dataset Information

0

C. neoformans small peptides SWATH-MS proteomics


ABSTRACT: Identification and relative quantification of small proteins present in the whole cell and C18 enrichment fractions of C. neoformans measured by DDA and SWATH-MS.

INSTRUMENT(S): TripleTOF 5600, LTQ Orbitrap Elite

ORGANISM(S): Cryptococcus Neoformans

SUBMITTER: Paige Erpf  

LAB HEAD: Benjamin Luke Schulz

PROVIDER: PXD022841 | Pride | 2024-02-26

REPOSITORIES: Pride

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Publications

Identification and characterisation of sPEPs in Cryptococcus neoformans.

Erpf Paige E PE   Chua Sheena M H SMH   Phung Toan K TK   Kerr Edward D ED   Rothnagel Joseph A JA   Schulz Benjamin L BL   Fraser James A JA  

Fungal genetics and biology : FG & B 20220323


Short open reading frame (sORF)-encoded peptides (sPEPs) have been found across a wide range of genomic locations in a variety of species. To date, their identification, validation, and characterisation in the human fungal pathogen Cryptococcus neoformans has been limited due to a lack of standardised protocols. We have developed an enrichment process that enables sPEP detection within a protein sample from this polysaccharide-encapsulated yeast, and implemented proteogenomics to provide insight  ...[more]

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