Proteomic analysis of in situ formalin-fixed paraffin-embedded (FFPE) human liver tissues

ABSTRACT: in situ proteomic analysis (combining laser microdissection of hepatocytes and mass spectrometry analysis) on formalin-fixed paraffin-embedded (FFPE) human liver tissues of 4 ZZ-Alpha 1-Antitrypsin Deficiency (AATD) pediatric patients and 4 ZZ-AATD adult patients that underwent liver transplantation versus 3 WT individuals infants and 4 adults, and compared proteins differentially expressed in ZZ pediatric and in ZZ adult AATD patients.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Liver

DISEASE(S): Alpha 1-antitrypsin Deficiency

SUBMITTER: Dupuy Jean-William  

LAB HEAD: Marion Bouchecareilh

PROVIDER: PXD022994 | Pride | 2021-09-09

REPOSITORIES: Pride