A chromatin basis for protein-RNA correlation in human cancer

ABSTRACT: This work describes a previously unreported link between the chromatin states and protein abundance in cancer. We curated and studied a novel cohort of human thyroid tumors that allowed us to identify chromatin features that directly regulate protein expression. We believe this is the first study to establish chromatin states that reflect protein abundances in human cancer.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Epithelial Cell, Thyroid Gland

DISEASE(S): Thyroid Cancer

SUBMITTER: Akshay Sanghi  

LAB HEAD: Michael Snyder

PROVIDER: PXD023078 | Pride | 2021-11-02

REPOSITORIES: Pride