Age-dependent changes in protein incorporation into collagen-rich tissues of mice by in vivo pulsed SILAC labelling

ABSTRACT: Collagen-rich tissues have poor reparative capacity that is further impaired with age, predisposing to common age-related disorders such as osteoporosis and osteoarthritis. We used in vivo pulsed SILAC labelling to quantify new protein incorporation into cartilage, bone, skin and plasma of mice across the life course.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Cartilage, Blood Plasma, Skin, Bone

SUBMITTER: Roman Fischer  

LAB HEAD: Roman Fischer

PROVIDER: PXD023180 | Pride | 2021-09-23

REPOSITORIES: Pride