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Mouse hippocampus RNA pull down LC-MS/MS

ABSTRACT: Antisense and sense probes of noncoding RNA GAS5 were used to perform the RNA pull down experiment on mouse hippocampus tissues. Then the proteins were identified by LC-MS/MS.

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Layer Of Hippocampus, Brain

SUBMITTER: Huawei MU

LAB HEAD: Xiaoyuan Song

PROVIDER: PXD023363 | Pride | 2021-09-09

REPOSITORIES: Pride

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Functional Network of the Long Non-coding RNA Growth Arrest-Specific Transcript 5 and Its Interacting Proteins in Senescence.

Wang Siqi S Ke Shengwei S Wu Yueming Y Zhang Duo D Liu Baowei B He Yao-Hui YH Liu Wen W Mu Huawei H Song Xiaoyuan X

Frontiers in genetics 20210310

Increasing studies show that long non-coding RNAs (lncRNAs) play essential roles in various fundamental biological processes. Long non-coding RNA growth arrest-specific transcript 5 (GAS5) showed differential expressions between young and old mouse brains in our previous RNA-Seq data, suggesting its potential role in senescence and brain aging. Examination using quantitative reverse transcription-polymerase chain reaction revealed that GAS5 had a significantly higher expression level in the old ...[more]

PMID: 33777096

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