KRAS Epitope Identification Immunopeptidomics

ABSTRACT: Utilizing computational epitope prediction and biochemical assays we predicted and identified high-affinity and/or high-stability KRAS peptides to high prevalence HLA class I molecules. Using single HLA class I allele lines and tumor cell lines in conjunction with MS spectrometry, selected mKRAS epitopes were identified as constituents of the HLA class I ligandome.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): T Cell

SUBMITTER: Beatriz Carreno  

LAB HEAD: Beatriz M. Carreno

PROVIDER: PXD024412 | Pride | 2021-05-29

REPOSITORIES: Pride