KRAS Epitope Identification Immunopeptidomics
Ontology highlight
ABSTRACT: Utilizing computational epitope prediction and biochemical assays we predicted and identified high-affinity and/or high-stability KRAS peptides to high prevalence HLA class I molecules. Using single HLA class I allele lines and tumor cell lines in conjunction with MS spectrometry, selected mKRAS epitopes were identified as constituents of the HLA class I ligandome.
INSTRUMENT(S): Orbitrap Fusion Lumos, Q Exactive HF
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): T Cell
SUBMITTER: Beatriz Carreno
LAB HEAD: Beatriz M. Carreno
PROVIDER: PXD024412 | Pride | 2021-05-29
REPOSITORIES: Pride
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