Proteomics

Dataset Information

0

KRAS Epitope Identification Immunopeptidomics


ABSTRACT: Utilizing computational epitope prediction and biochemical assays we predicted and identified high-affinity and/or high-stability KRAS peptides to high prevalence HLA class I molecules. Using single HLA class I allele lines and tumor cell lines in conjunction with MS spectrometry, selected mKRAS epitopes were identified as constituents of the HLA class I ligandome.

INSTRUMENT(S): Orbitrap Fusion Lumos, Q Exactive HF

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): T Cell

SUBMITTER: Beatriz Carreno  

LAB HEAD: Beatriz M. Carreno

PROVIDER: PXD024412 | Pride | 2021-05-29

REPOSITORIES: Pride

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