Ontology highlight
ABSTRACT:
INSTRUMENT(S): Agilent instrument model, 6520 Quadrupole Time-of-Flight LC/MS
ORGANISM(S): Homo Sapiens (human) Bos Taurus (bovine)
SUBMITTER: Mark Condina
LAB HEAD: Peter Hoffmann
PROVIDER: PXD024489 | Pride | 2021-07-08
REPOSITORIES: Pride
Young Clifford C Condina Mark R MR Briggs Matthew T MT Moh Edward S X ESX Kaur Gurjeet G Oehler Martin K MK Hoffmann Peter P
Frontiers in chemistry 20210611
Protein glycosylation is a common post-translational modification that modulates biological processes such as the immune response and protein trafficking. Altered glycosylation profiles are associated with cancer and inflammatory diseases, as well as impacting the efficacy of therapeutic monoclonal antibodies. Consisting of oligosaccharides attached to asparagine residues, enzymatically released <i>N-</i>linked glycans are analytically challenging due to the diversity of isomeric structures that ...[more]