Global and phospho-proteome of Hek293T treated with kinase inhibitors

ABSTRACT: We examine the changes in HEK293T overexpressing alpha-synucleinA53T-GFP when treated with kinase inhibitors (SB203580, GF109203X,SB202190, Enzastaurin, VX-745). Main findings is altered protein translation, with an increase in lysosomal proteins for all compounds save VX-745

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture, Early Embryonic Cell

DISEASE(S): Parkinson's Disease

SUBMITTER: Alexander Svanbergsson  

LAB HEAD: Jia-yi Li

PROVIDER: PXD024508 | Pride | 2021-07-05

REPOSITORIES: Pride