An ERK5-KLF2 signalling module regulates early embryonic gene expression dynamics and stem cell rejuvenation

ABSTRACT: CCE mESCs were transfected with either empty pCAGGS vector or HA-MEK5DD (S311D T315D) construct for 48 hours. 24 hours prior to lysis, mESCs were either treated with 10uM AX15836 or DMSO control, and transfected mESCs selected with puromycin. Conditions were performed in triplicate.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Embryonic Stem Cell

DISEASE(S): Disease Free

SUBMITTER: Greg Findlay  

LAB HEAD: Greg Findlay

PROVIDER: PXD024679 | Pride | 2021-03-18

REPOSITORIES: Pride