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Identification of Siglec-7-ligand candidates on JVM-3 human B cell line by proximity labeling

ABSTRACT: Siglec-7 is a member of Siglec family of glycan recognition proteins involved in the regulation of natural killer (NK) cell activities. We found Siglec-7 ligand is highly expressed on JVM-3, a B cell chronic lymphocytic leukemia (B-CLL) cell line. In this experiment, we attempted at identifying the ligands of Siglec-7 on JVM-3 by applying the proximity labeling method we developed (Chang L et al., J Proteome Res. 2017, 16:3929-41).

INSTRUMENT(S): LTQ Orbitrap Elite

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): B Cell

SUBMITTER: Yi-Ju Chen

LAB HEAD: Takashi Angata

PROVIDER: PXD024690 | Pride | 2022-05-31

REPOSITORIES: Pride

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Identification of Siglec-E-ligand candidates on BCL-1 mouse B cell line by proximity labeling

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