Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion Lumos, Q Exactive HF
ORGANISM(S): Homo Sapiens (human) Drosophila Melanogaster (fruit Fly)
SUBMITTER: Sergey Vakhrushev
LAB HEAD: Sergey Vakhrushev
PROVIDER: PXD024767 | Pride | 2021-04-07
REPOSITORIES: Pride
Bagdonaite Ieva I Thompson Andrew J AJ Wang Xiaoning X Søgaard Max M Fougeroux Cyrielle C Frank Martin M Diedrich Jolene K JK Yates John R JR Salanti Ali A Vakhrushev Sergey Y SY Paulson James C JC Wandall Hans H HH
Viruses 20210325 4
Enveloped viruses hijack not only the host translation processes, but also its glycosylation machinery, and to a variable extent cover viral surface proteins with tolerogenic host-like structures. SARS-CoV-2 surface protein S presents as a trimer on the viral surface and is covered by a dense shield of N-linked glycans, and a few O-glycosites have been reported. The location of O-glycans is controlled by a large family of initiating enzymes with variable expression in cells and tissues and hence ...[more]