EAE Optic Nerve Injections with LPC 18:1 (iTRAQ)

ABSTRACT: EAE mice were injected with LPC 18:1 at the optic nerve when they exhibited a clinical score of 2. Visual function was assessed via pattern electroretinogram and optic nerves were harvested 12 days post optic nerve injection. Three different visual recovery pathways were observed: 1) No-injection control (no recovery in visual function), 2) Low recovery visual function, 3) High recovery visual function and 4) No change in visual function.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Optic Nerve

DISEASE(S): Multiple Sclerosis

SUBMITTER: Sanjoy Bhattacharya  

LAB HEAD: Sanjoy Bhattacharya

PROVIDER: PXD024966 | Pride | 2022-02-17

REPOSITORIES: Pride