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Metaproteomic profiling of the intestinal microbiota of SARS-CoV-2 infected patients

ABSTRACT: Application of a mass spectrometry -based approach to assess the gut microbiota composition and the associated metaproteomic functionality in patients with intestinal COVID-19 infection

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Archaea Bacteria Viruses Eukaryota (eucaryotes)

SUBMITTER: Jean ARMENGAUD

LAB HEAD: Jean Armengaud

PROVIDER: PXD024990 | Pride | 2022-09-01

REPOSITORIES: Pride

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Taxonomical and functional changes in COVID-19 faecal microbiome could be related to SARS-CoV-2 faecal load.

Grenga Lucia L Pible Olivier O Miotello Guylaine G Culotta Karen K Ruat Sylvie S Roncato Marie-Anne MA Gas Fabienne F Bellanger Laurent L Claret Pierre-Géraud PG Dunyach-Remy Catherine C Laureillard Didier D Sotto Albert A Lavigne Jean-Philippe JP Armengaud Jean J

Environmental microbiology 20220509 9

Since the beginning of the pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) the gastrointestinal (GI) tract has emerged as an important organ influencing the propensity to and potentially the severity of the related COVID-19 disease. However, the contribution of the SARS-CoV-2 intestinal infection on COVID-19 pathogenesis remains to be clarified. In this exploratory study, we highlighted a possible link between alterations in the composition of the gut microbio ...[more]

PMID: 35506300

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