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Human corneal stroma proteomic profile of myopic eyes

ABSTRACT: This is a cross-sectional case-control study. Study subjects of generalized myopic patients in preparation for small incision lenticule extraction (SMILE) surgery were recruited and divided into low and high myopia subgroups.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cornea, Keratocyte

DISEASE(S): Myopia

SUBMITTER: Yan Wang

LAB HEAD: Yan Wang

PROVIDER: PXD025145 | Pride | 2022-02-17

REPOSITORIES: Pride

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Publications

Novel Corneal Protein Biomarker Candidates Reveal Iron Metabolic Disturbance in High Myopia Eyes.

Chen Jingyi J Wu Wenjing W Wang Zhiqian Z Zhai Chuannan C Deng Baocheng B Alzogool Mohammad M Wang Yan Y

Frontiers in cell and developmental biology 20211001

Myopia is a major public health concern with increasing global prevalence and is the leading cause of vision loss and complications. The potential role of the cornea, a substantial component of refractive power and the protective fortress of the eye, has been underestimated in the development of myopia. Our study acquired corneal stroma tissues from myopic patients undergoing femtosecond laser-assisted small incision lenticule extraction (SMILE) surgery and investigated the differential expressi ...[more]

PMID: 34660571

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microRNA profiling in the aqueous humor of highly myopic eyes by next generation sequencing

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2023-07-12 | PXD043196 | Pride

High throughput gene expression analysis identifies reliable expression markers of human corneal endothelial cells.

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Evaluation of MicroRNA Expression Profiles for Form-Deprivation Myopia in Mouse

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