EAE Optic Nerves Injected with LPC 18:1 + Isobaric C13-His

ABSTRACT: EAE mice were injected with LPC 18:1 and Isobaric C13-His at the optic nerve when they exhibited a clinical score of 2. Visual function was assessed via pattern electroretinogram and optic nerves were harvested 12 days post optic nerve injection. Optic nerves were processed for mass spectrometry to identify the integration of C13-His in newly synthesized proteins.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Optic Nerve

DISEASE(S): Multiple Sclerosis

SUBMITTER: Sanjoy Bhattacharya  

LAB HEAD: Sanjoy Bhattacharya

PROVIDER: PXD025176 | Pride | 2022-02-17

REPOSITORIES: Pride